Discrepancy in the results of Y chromosome microdeletions in an Iranian population
نویسندگان
چکیده
منابع مشابه
Frequency of Y Chromosome Microdeletions in Azoospermic and Oligospermic Iranian Infertile Men
Background and Aims: Azoospermia factor (AZF) region of the Y-chromosome has several genes which are responsible for normal spermatogenesis. Microdeletions of these genes are associated with azoospermia and oligospermia. These microdeletions are too small to be detected by karyotyping. They can be easily identified using polymerase chain reaction. The aim of this study is to determine the frequ...
متن کاملprevalence of y chromosome microdeletions in iranian infertile men
this study was designed to determine the frequency of y chromosome azf (azoospermia factor ) subregions, microdeletions in patients with idiopathic nonobstructive azoospermia and severe oligozoospermia. subjects included 40 men who had been referred to infertility clinics for assisted reproduction, 37 were azoospermic and 3 had severe oligospermia. medical history and physical exam revealed no ...
متن کاملO-7: Y Chromosome Microdeletions Are Not Associated with Spontaneous Recurrent Pregnancy Loss in A Sinhalese Population in Sri Lanka
Background: Many advances have been made in reproductive medicine yet the spontaneous loss of a pregnancy remains the most common complication of pregnancy. The aetiology of spontaneous recurrent pregnancy loss (RPL) is multifactorial. Y chromosome microdeletions are found in approximately 7% of men with low sperm counts and, compared to the general population, a higher frequency of spontaneous...
متن کاملthe prevalence of y chromosome microdeletions in iranian infertile men with azoospermia and severe oligospermia
objective: microdeletions of the y chromosome long arm are the most common molecular genetic causes of severe infertility in men. they affect three regions including azoospermia factors (azfa, azfb and azfc), which contain various genes involved in spermatogenesis. the aim of the present study was to reveal the patterns of y chromosome microdeletions in iranian infertile men referred to royan i...
متن کامل[Y chromosome microdeletions in male infertility].
A genetic basis of infertility may exist in many men currently classified as having idiopathic infertility. Approximately 7% of infertile men harbour submicroscopic deletions of the Y chromosome that are not detectable on routine karyotype. Two candidate gene families, namely the RNA-binding motif-containing gene family, and the deleted-in-azoospermia gene family, have been cloned by deletion m...
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ژورنال
عنوان ژورنال: Journal of Human Reproductive Sciences
سال: 2011
ISSN: 0974-1208
DOI: 10.4103/0974-1208.92295